EUTRAIN project has ended

The “European Translational training for Autoimmunity & Immune manipulation Network” project has ended as per 31/12/2015. The final and financial reports have been submitted. We thank all EUTRAIN colleagues for their participation and the great collaboration in a wonderful project!

‘Gender gap’ in science – fact or history?

By Alessandra Petrelli & Nienke de Graeff

What comes to your mind when you think of a debate about differences between men and women in science? A topic of discussion for a feminist reunion? An outdated problem? That is what you would think in the year 2014; however, there are actually still differences. The question is: what determines these differences? And what should you do with them? As turns out, the topic is still sensitive and sparks a lively discussion.

                On Tuesday November 18th 2014, we organized a symposium on this topic in the University Hall of the University of Utrecht, as a part of the FP7 MarieSkłodowska-CurieProject EUTRAIN and in collaboration with the Eureka Institute. 30 Italian and Dutch scientists at different stages in their career took part in the debate: students, PhD candidates, post docs, young principal investigators and professors. The central question was: is there still inequality between men and women in science? If so, in what ways is it expressed in the everyday working life? Participants voted on ten provocative statements on the topic and discussed four general themes: (i) qualities a scientist-to-be needs to have to succeed in science and if those qualities are gender-related, (ii) parental leave and its distribution between men and women, (iii) the ratio of men and women in top positions and (iv) possible effects of the current policies on the future.

The goal of this meeting was to bring the topic up for discussion and create awareness, with a focus on exchange of experiences and opinions between scientists with varying amounts of working experience. Many discussion points and divergent views were addressed which we tried to summarize and report herein. When one faces the facts, there is still quite some inequality when it comes to these topics, but this is mainly felt to be a problem by women at a later stage in their career, whilst students actually do not see any clouds on the horizon. Participants agreed that men and women are equal, but not the same: indeed female characteristics result in a different type of leadership, more team-based and less individualist; men and women can achieve the same but, according to the female professors, women have to pay a higher price (renounce/neglect family) or put in more effort to get there. Nonetheless, the most determining factor for success was judged to be passion, a cross-gender quality. The pregnancy issue was widely debated. It is still a problem for some employers when a female scientist in their group gets or is planning to become pregnant. Is it really possible that a few months of maternity leave can affect scientific production? The overall reply was no. Interestingly, it was considered unfair that men get only two days of parental leave when their child is born, whereas women get three to four months. A recurrent subject of discussion was the still small fraction of female professors inEurope, even in female-dominated fields like linguistics, cultural science or the health sector. The majority of the female scientists said that time alone will not be enough to equal out the differences between men and women – it would take too long. But what should be done? An obvious solution is installing gender quotas, specifying a minimum percentage of women in top positions. Opinions were divided on this topic. A part of the participants was strongly in favour, as long as quality is assured and the chosen percentage represents the distribution in the field. Male participants supported the idea that one should not be selected based on gender but rather on quality and that benefits for working mothers should be applicable to fathers too.

Before and after discussion the opinions were polled; the most remarkable shift was noticeable in the opinion of the students, who were more conscious of the issue (or discouraged, as someone remarked) at the end of the discussion.

All in all, the topic is broad, the opinions diverse and the arguments abundant, but one thing was beyond dispute after the symposium: the discussion on gender differences is still a timely and sensitive issue. It is a difficult topic to address, in which personal experiences and emotions are prone to be at the foreground. But whether you agree or disagree – in the end, the debate revolves around the feelings and experience of a considerable part of society; thus, a topic worth discussing.

Welcome to Berlin for the EUTRAIN fellow days – November 6-7, 2014





Dear all,

This time, the EUTRAIN fellow days will take place in Berlin at the Deutsches Rheuma-Forschungszentrum (DRFZ). Two days of talks and discussions about our projects and the “how to communicate in science even better” training session are on the list. We will hear about a real-live example of bench to bedside translation in lupus therapy and learn about data evaluation in medical and biological research. On Thursday evening, we will do a tour through the Berlin Museum of Medical History.

Unfortunately, there will be no time left to enjoy rainy, cold November weather in Berlin. No, seriously, the weather is supposed to be really nice and to treat ourselves for the hard work, some Berlin-Friday-evening-fun is waiting for us after the last session.

We are very much looking forward to having all of you here next week!

Hyun-Dong Chang, Patrick Maschmeyer and Eva Kreiss

DRFZ Berlin

Final Program November Meeting Berlin


Welcome Dr. Elise van de Putte

We would like to introduce to you Dr. Elise van de Putte. Dr. Van de Putte has agreed to serve as an independent ethics advisor and reviewer for EUTRAIN. She is an outstanding expert in this area as she is the chair of the only Institutional review board in the Netherlands that is primarily focused on children. Apart from her role in the board, Dr. Van de Putte is also a practicing clinician (pediatrics) and an excellent clinical researcher who has published in the top journals in her field, including the Lancet. We are very happy to have Dr. van de Putte on board for EUTRAIN. She is available for advice for all ESR’s and PI’s and will review any ethical issues that might be raised within EUTRAIN.

Short bio Elise van der Putte

Elise van de Putte CV Eutrain 2014


Ilona’s secondment in Lyon

EUtrain secondment – Hospital of Lyon – November 2013
Fellow visited: Paola Bonaventura
Field of work of visited fellow: Biomolecular
Length of stay: 3 days


Description of carried out activities:

  1. Together we took a close look to the clinical approach of the arthritic disease:
  • Diagnose (Histology, questioning, imaging )
  • Treatment of patients at different stages of the disease

We had the opportunity to follow all the process from the hand of the professor Miossec assistant, A.M. Neamt. We also had the opportunity to see how a US scanner was used on adult patients with arthritis (Dr. T. Roland), which was of great value to learn more about the expressions of the disease and the identification of human anatomy.

  1. Paola also showed me some of the work carried out in the laboratory with the healthy and sick tissues they receive from the hospital. Her research is centered in seeing if the use of metals can modulate the inflammation and the growth of sick cells and interacting with the progression of the pathology of Rheumatoid arthritis

Apart from this Paola also explained the principles of immunology, which was very important for my better understanding of the whole picture.

Evaluation of the experience:

            The experience was very enriching and interesting!  It helps a lot to understand the fellow partners and the environment you are working in. Working in a multidisciplinary team is truly a great thing. On a personal level it is also very nice to get to know the people closer.

Alessandra Petrelli’s secondment in Milan

‘Autumn in the Netherlands is characterized by unsettled weather’. This is what I was told when I first arrived in Utrecht! Being southern Italian, I rapidly started thinking to a way to still enjoy nice sunny days before the onset of winter. That’s how I ended up in a fruitful collaboration with the Milan Group! It’s a joke, of course!

The truth is that last summer I had preliminary interesting data on a cell population enriched in the synovial fluid of Juvenile Idiopathic Arthritis that seemed to be highly cytotoxic, thus a good potential candidate for a cell-depletion strategy. However, phenotypic and functional characterization of the population of interest at a single cell level was still missing. Being aware of the over 20-year experience of Maria Grazia Roncarolo and Manuela Battaglia’s group (PIs-ESR08) in single cell T cell cloning, Berent and I thought that a secondment in Milan would have been a good opportunity to learn this technique for the whole Prakken’s group and for my project itself. Then I spent 2 months (Sept and Oct 2013) at San Raffaele Scientific Institute in Milan and, thanks to Maria Grazia and Manuela’s tips I was able to generate single cell clones of the population of interest. I want to thank also Bechara (ESR08) for his help in the lab and for the nice collaboration we set up.

Financially everything went surprisingly smooth: expenses for 2-month room and board were pretty high but I was fully reimbursed by the EUtrain grant.

To conclude, I fully suggest to go on a secondment in other Institutes within the Eutrain Network. It’s fun and useful for your projects!

Alessandra Petrelli (ESR02).